Tuesday, 13 September 2011

I am working on Sodium arsenite toxicity. It can enter the body of fish through different routes, such as gill, skin, etc. However, the accumulation and distribution patterns of toxic metals in fish tissues are dependent on their uptake and elimination rates.

Chemical Name and Synonyms:
meta-arsenite; Arsenious acid, sodium salt
Sodium arsenite; Sodium
Chemical Family:
Metal saltChemical Formula:

TOXICOLOGICALPROPERTIES AND HEALTH DATA
Toxicological Data:
LC 50 value

In contact with eyes:
tearing, possible damage to conjunctiva.
Harmful. Causes irritation, redness,
Ingested:
irritation and blood, heart, liver and kidney effects. Toxic
symptoms include nervousness, thirst, acute nausea and
vomiting, diarrhea, cyanosis, collapse and death. Estimated
lethal dose, 120 mg. Soluble arsenic (As) compounds are
considered poisonous to humans; inorganic arsenic is more
toxic than organic arsenic, as organic arsenic is excreted
more rapidly than inorganic; arsenic 5+ is excreted more
rapidly than arsenic 3+, makng the 3+ form more toxic.
Effects of Chronic Exposure to Product:
Chronic overexposure to arsenic compounds causes skin
and eye irritation, peripheral neuritis of the hands and feet,
increased risk of lung and skin cancer, damage to liver, kidneys,
and nervous system. Symptoms of chronic exposure
include weight loss, nausea, diarrhea, weakness, loss of appetite, garlic odour to tthe breath, bronzing of the skin, dermatitis,
skin lesions.
Carcinogenicity:
human carcinogen (ACGIH, IARC, NTP)
Carcinogenicity designation A1, confirmed
Teratogenicity:
tests (RTECS No. CG3675000)
Developmental abnormalities in animal
Reproductive Effects:
Harmful effects in animal testingMutagenicity: May alter genetic material.
Poisonous; may be fatal. Causes severe stomach
: (Fish) 28mg/l
NaAsO2